Notice: we have updated rSNPBase to rVarBase, new features and detailed information could be found at http://rv.psych.ac.cn
About rSNPBase
rSNPBase is a database that provides reliable, comprehensive, and user-friendly regulatory annotations on rSNPs. It will assist researchers in selecting candidate SNPs for further genetic studies (especially for QTL studies), identifying causal variants of certain phenotypes, and exploring in-depth molecular mechanisms.
An example for database usagerSNPBase is different from previous SNP annotation databases on such features: 1) To improve reliability, rSNPBase annotated SNPs with reference to experimentally supported regulatory elements other than predicted data. 2) rSNPBase focuses on rSNPs involved in a wide range of regulation types, including proximal and distal transcriptional regulation and post-transcriptional regulation and identifies their potentially regulated genes. 3) Linkage disequilibrium (LD) correlations between SNPs were analyzed so that the regulatory feature is annotated to SNP-set rather than a single SNP. 4) The spatio-temporal and experimental eQTL labels are provided in rSNPBase for a better annotation.
Detailed data infomation is shown on Data content
Citation: Guo, L., Du, Y., Chang, S., Zhang, K., & Wang, J. (2014). rSNPBase: a database for curated regulatory SNPs. Nucleic Acids Res, 42 (D1): D1033-D1039. doi: 10.1093/nar/gkt1167. Link